Panfeng Fu Selected Research

Therapeutics

1/2020	Neonatal therapy with PF543, a sphingosine kinase 1 inhibitor, ameliorates hyperoxia-induced airway remodeling in a murine model of bronchopulmonary dysplasia.
12/2019	Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung.
1/2018	Sphingolipids Signaling in Lamellipodia Formation and Enhancement of Endothelial Barrier Function.
8/2011	Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression.

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Panfeng Fu Research Topics

Disease

13	Pneumonia (Pneumonitis) 05/2024 - 01/2008
12	Acute Lung Injury 05/2024 - 07/2007
11	Lung Injury 05/2024 - 01/2008
11	Inflammation (Inflammations) 01/2020 - 01/2005
11	Ventilator-Induced Lung Injury 01/2018 - 01/2008
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2024 - 04/2013
5	Infections 03/2021 - 01/2005
5	Neoplasms (Cancer) 01/2018 - 12/2004
4	Sepsis (Septicemia) 05/2024 - 11/2010
4	Hyperoxia 01/2022 - 01/2016
4	Fibrosis (Cirrhosis) 03/2020 - 04/2013
3	Bronchopulmonary Dysplasia 09/2021 - 01/2020
3	Lung Diseases (Lung Disease) 03/2020 - 12/2016
3	Idiopathic Pulmonary Fibrosis 03/2020 - 04/2013
3	Myocardial Infarction 01/2006 - 01/2005
2	Edema (Dropsy) 05/2024 - 08/2011
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2024 - 03/2022
2	Asthma (Bronchial Asthma) 01/2021 - 10/2013
2	Pulmonary Edema 11/2010 - 06/2010
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 11/2010 - 04/2009
1	Mycoses (Diseases, Fungus) 01/2024
1	Neuroinflammatory Diseases 10/2023
1	Chronic Obstructive Pulmonary Disease (COPD) 03/2022
1	Eczema 01/2021
1	Tobacco Use Disorder (Nicotine Dependence) 01/2021
1	Sleep Deprivation 01/2021
1	Rhinitis 01/2021
1	Airway Remodeling 01/2020
1	Pathologic Processes 01/2020
1	Bacterial Infections (Bacterial Infection) 12/2019
1	Necrosis 01/2019
1	Cystic Fibrosis (Mucoviscidosis) 01/2018
1	Respiratory Insufficiency (Respiratory Failure) 01/2018
1	Vascular Remodeling 12/2017
1	Hypertrophy 12/2017

Drug/Important Bio-Agent (IBA)

7	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 12/2011
7	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2020 - 08/2011
5	Bleomycin (Blenoxane)FDA LinkGeneric 01/2024 - 04/2013
5	Proteins (Proteins, Gene)FDA Link 11/2023 - 11/2010
5	CytokinesIBA 11/2023 - 10/2013
5	LipidsIBA 01/2020 - 07/2007
5	oxidized- L- alpha- 1- palmitoyl- 2- arachidonoyl- sn- glycero- 3- phosphorylcholineIBA 05/2012 - 01/2008
4	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2022 - 01/2016
4	sphingosine kinaseIBA 09/2021 - 04/2013
4	SphingolipidsIBA 01/2018 - 12/2016
3	indium-bleomycinIBA 01/2024 - 04/2013
3	SphingosineIBA 09/2021 - 01/2016
3	Phosphates (Orthophosphate)IBA 09/2021 - 12/2019
3	Thrombin FDA Link 01/2020 - 01/2010
3	lysophosphatidic acidIBA 01/2020 - 10/2013
3	EnzymesIBA 12/2016 - 12/2011
3	Phospholipids (Phosphatides)FDA LinkGeneric 04/2011 - 01/2008
3	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2010 - 07/2007
2	Amifostine (Ethyol)FDA LinkGeneric 01/2024 - 12/2011
2	Oxygen (Dioxygen)IBA 09/2021 - 12/2011
2	Histones (Histone)IBA 01/2019 - 01/2017
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 11/2010
2	sphingosine 1-phosphate lyase (aldolase)IBA 01/2018 - 08/2011
2	NADP (NADPH)IBA 12/2017 - 04/2013
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 05/2017 - 05/2014
2	LyasesIBA 01/2017 - 01/2016
2	Small Interfering RNA (siRNA)IBA 01/2016 - 12/2015
2	PaxillinIBA 12/2015 - 05/2015
2	Lysophosphatidic Acid ReceptorsIBA 12/2013 - 10/2013
2	LipopolysaccharidesIBA 12/2011 - 01/2008
2	Iloprost (Ventavis)FDA Link 01/2010 - 12/2009
2	TIE-2 Receptor (Receptor, TIE 2)IBA 01/2006 - 01/2005
2	C-Reactive ProteinIBA 01/2006 - 01/2005
1	3- (2,4- dichloro- 5- methoxyphenyl)- 2- sulfanyl- 4(3H)- quinazolinoneIBA 05/2024
1	Nicotinamide PhosphoribosyltransferaseIBA 05/2024
1	Sirtuin 1IBA 01/2024
1	NAD (NADH)IBA 01/2024
1	C.I. Fluorescent Brightening Agent 28IBA 01/2024
1	1- (4- chlorophenylhydrazono)- 1- (4- chlorophenylamino)- 3,3- dimethyl- 2- butanoneIBA 11/2023
1	Cardiolipins (Cardiolipin)IBA 03/2022
1	SmokeIBA 03/2022
1	Caffeine (No Doz)FDA LinkGeneric 01/2021
1	BCG Vaccine FDA Link 01/2021
1	LysophospholipidsIBA 01/2020
1	PF-543IBA 01/2020
1	Peptide Hydrolases (Proteases)FDA Link 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Epithelial Sodium ChannelsIBA 12/2019
1	MucinsIBA 12/2019
1	RNA (Ribonucleic Acid)IBA 12/2019
1	Phospholipase DIBA 01/2019
1	Mitochondrial DNA (mtDNA)IBA 01/2019
1	Protein Kinase CIBA 01/2019
1	Phosphatidic Acids (Phosphatidic Acid)IBA 01/2019
1	1-dodecylpyridoxal (PLD)IBA 01/2019
1	CeramidesIBA 01/2018
1	fatty aldehydeIBA 01/2017
1	phosphorylethanolamine (phosphoethanolamine)IBA 01/2017
1	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 01/2017
1	AldehydesIBA 01/2017
1	PhloretinIBA 01/2017

Therapy/Procedure

7	Artificial Respiration (Mechanical Ventilation) 01/2018 - 01/2008
4	Therapeutics 01/2020 - 08/2011
2	Mechanical Ventilators (Ventilator) 01/2016 - 01/2008
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2018